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Multifunctional activity of bioactive peptides and their positive impacts on animal body

1. What are Bio-Active Peptides

Bio-Active Peptides are short-chain amino acids that have a very specific function and target. In all proteins, there are active components or parts of the protein chain that actually perform the function of that protein. They have a specific active site, and the entire protein functions by the active portion making contact with its unique and matching target receptor.

Although some BP exist freely in its natural source, the vast majority of known BP are encrypted in the structure of the parent proteins and released mainly by enzymatic processes. Some BP have been prepared by chemical synthesis.

2. How do they work in bloodstream?

The short chain peptides gives them an advantage of stability over long chain peptides. Short chain peptides are replicated more efficiently and there is no issues of collapsing during absorption. They are rapidly absorbed into the bloodstream. From there, depending on their function, they either enter the cell directly, move to their target site or reside on the cell itself, perform their job on and between the cells. Some act to start a pathway or process; others act as signal mechanism; and some simply relay or convey information to other parts of a cell.

3. How do your animal benefits from bioactive peptides?

BP play a significant role in animal health by affecting the digestive, immune, cardiovascular, immune and nervous systems. BP are considered the new generation of biologically active regulators; they can prevent oxidation and microbial degradation in foods and also improve the treatment of various diseases and disorders. The growing interest in BP has incentivized the scientific community and the feed industry to exploring the development of new feed additives and functional ingredients based on these peptides.

In animal production, there are so many scientific researches on the positive impacts of BP in

  • Improving feed efficiency and animal growth performance

  • Maintaining better physiological status

  • Stimulating immunity system and excellent defence to stress and pathogens

The most well known activities are as below:

Increase feed intake

Stressful conditions in the raising environment and animal health status may reduce feed intake. Bioactive Peptides & Free Amino Acids in Poultry Protein Hydrolysates help enhance feed intake, especially during stressful time.

  • Small peptides and free amino acids do condition of taste perception

  • Peptides influence appetite through their actions on the hormone that regulates feed intake

The result is better growth performance and improved feed efficiency

Offer better nutritional value

Balanced free amino acid profiles and high content of digestible Protein (up to 90- 95%) with high bioavailability helps increase the feed efficiency. More stable and smaller size of short chain peptides are easy to be adsorbed and take active in the digestive tract, too.

Stimulate immune system

Due to Peptides' critical role in metabolism as well as the ability of intestine membrane penetration of short peptides, they help stimulate passive immunity in the intestinal lumen and maintain optimal physical performance of your animal through enhancing antimicrobial, antioxidant, antihypertensive, and immunomodulatory functions…

  • Antioxidants: Digestion studies in vitro have provided evidence that a mixture of peptides (2–4 amino acid residues) obtained from certain food proteins using human digestive enzymes under physiological conditions possess potent antioxidant activity (Zhu et al., 2008).

  • Antimicrobials: Antimicrobial properties is the most crucial, which are used as the first chemical barrier against microbial attack, being synthesized in response to bacterial infections. Antioxidant activity of bioactive peptides can also be attributed to their radical scavenging, inhibition of lipid peroxidation and metal ion chelation properties of peptides.

Peptides acting on the bacterial membrane

Peptides acting on the bacterial membrane

These above functions result in better animal physiological status and excellent defence to stress and pathogens

4. Where do Bio-Active Peptides come from?

In short, they come from protein (and in particular in higher concentration of colostrum). They are found in all animal sources (in muscle and blood), dairy (the milks from animal or plant), and egg sources, fish sources (like animal), and plant sources (the protein portions such as soy, pea, wheat, hemp, rice, etc.)

There are several methods to produce BP and one of the most effective method is protein hydrolysis: chemical hydrolysis, enzyme hydrolysis... The enzymes have been selected by NAN to generate wide range of bioactive peptide. The enzymatic hydrolysis process is today recoginized the most efficient and reliable process which could yield the maximum of bioactive peptides from marine raw materials (Zarei et al., 2012).

There are many factors that affect bioactive peptide content & quality, and choosing the good and cosistent BP from qualified provider will decide the efficacy of this strategic feed ingredient.


Protein Hydrolysates are effective solutions to formulate functional and specific feeds as well as to reduce the dependence to marine raw materials.

The research and results of the current study indicate that BP from Dietary marine protein hydrolysate can improve growth performance, feed utilization, digestibility, innate immunity and disease resistance. Bioactive peptides may be considered as an Alternative To Antibiotics Growth Promoters.

At NAN Group, we guarantee that product consistency comes from mono-species and refined raw material that ensure best BP quality from batch-to-batch.

#bioactivepeptides #marineproteinhydrolysates

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